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Hirst was always interested in the connection between science and art. He often injected elements of medicine into his works, such as medicines, medicine cabinets and pills; His "dot" drawings simulate medical color codes. Hirst also often USES materials from daily life, such as office desks, chairs and cigarettes, which can be seen in The work "The Acquired Inability to Escape". Although there is no human as the protagonist in the work, it implies the absence of human beings. We are faced with an artificial environment, and the design of clean modern glass Windows also reminds us that this is an aquarium or a zoo. Although hirst wanted to show the concept of escape through the cigarette in the window, it was impossible to escape through the space where the white collar existed because the window was sealed. A swivel chair and a desk, typical office elements, are used as symbols of human existence, like anthropological artifacts. Hirst also suggests that life cannot be reduced to functionality in a sterile and artificial environment.

Hirst was also interested in the finitude of biological life. One of his most famous works, "Away From the Flock" (1994), is a lamb soaked in formaldehyde. In "Girls, Who Like Boys, Who Like Boys, Who Like Boys, Who Like Girls, Who Like Boys, Who Like Girls, Like Girls, Like Boys, 2006", the surface is covered with very beautiful butterflies, but there are also worrying razors. Hearst reminds the audience that life is short. Although the butterfly makes the surface of the painting very beautiful, the razor conjures up images of the moon in the mirror, reminding us of the presence of danger and the impermanence of material beauty. The title of the work is taken from a 1995 song "Boys and Girls" by obscure, a British pop group, and the colors on the canvas highlight the complexity of the physical attraction.

Hirst is internationally recognized as the most influential artist in Britain. More recently, he has been working to promote contemporary art by expanding new exhibition Spaces in London and Gloucestershire. Meanwhile, he plans to build a museum in Gloucestershire.

In 2003, a sculpture by Hirst entitled "Charity" sold for £1m, the first time a single work by a living British artist has sold for so much.

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